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IQGAP1 Interacts with Components of the Slit Diaphragm Complex in Podocytes and Is Involved in Podocyte Migration and Permeability In Vitro

IQGAP1 is a scaffold protein that interacts with proteins of the cytoskeleton and the intercellular adhesion complex. In podocytes, IQGAP1 is associated with nephrin in the glomerular slit diaphragm (SD) complex, but its role remains ill-defined. In this work, we investigated the interaction of IQGA...

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Detalles Bibliográficos
Autores principales: Rigothier, Claire, Auguste, Patrick, Welsh, Gavin I., Lepreux, Sébastien, Deminière, Colette, Mathieson, Peter W., Saleem, Moin A., Ripoche, Jean, Combe, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360763/
https://www.ncbi.nlm.nih.gov/pubmed/22662192
http://dx.doi.org/10.1371/journal.pone.0037695