Dopamine Induced Neurodegeneration in a PINK1 Model of Parkinson's Disease

BACKGROUND: Parkinson's disease is a common neurodegenerative disease characterised by progressive loss of dopaminergic neurons, leading to dopamine depletion in the striatum. Mutations in the PINK1 gene cause an autosomal recessive form of Parkinson's disease. Loss of PINK1 function cause...

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Detalles Bibliográficos
Autores principales: Gandhi, Sonia, Vaarmann, Annika, Yao, Zhi, Duchen, Michael R., Wood, Nicholas W., Abramov, Andrey Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360782/
https://www.ncbi.nlm.nih.gov/pubmed/22662171
http://dx.doi.org/10.1371/journal.pone.0037564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360782/
https://www.ncbi.nlm.nih.gov/pubmed/22662171
http://dx.doi.org/10.1371/journal.pone.0037564

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