Activation of β-Catenin by Oncogenic PIK3CA and EGFR Promotes Resistance to Glucose Deprivation by Inducing a Strong Antioxidant Response

Glucose is an essential fuel for cell survival and its availability limits aberrant cellular proliferation. We have hypothesized that specific cancer mutations regulate metabolic response(s) to glucose deprivation (GD). By means of somatic knock-in cellular models, we have analyzed the response to g...

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Detalles Bibliográficos
Autores principales: Cardone, Luca, Bardelli, Alberto, Avvedimento, Vittorio Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360841/
https://www.ncbi.nlm.nih.gov/pubmed/22662165
http://dx.doi.org/10.1371/journal.pone.0037526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360841/
https://www.ncbi.nlm.nih.gov/pubmed/22662165
http://dx.doi.org/10.1371/journal.pone.0037526

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