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The association of an adenine insertion variant in the 5’UTR of the endothelin-1 gene with hypertension and orthostatic hypotension

INTRODUCTION: An adenine insertion polymorphism in the 5’ untranslated region of the endothelin-1 gene is functional and increases the expression of endothelin mRNA and protein in the insertion homozygote. In the present study we hypothesized that this functional polymorphism might be associated wit...

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Detalles Bibliográficos
Autores principales: Fan, Xiao-han, Wang, Hu, Gao, Ling-gen, Sun, Kai, Zhou, Xiang-liang, Hui, Ru-tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361033/
https://www.ncbi.nlm.nih.gov/pubmed/22661993
http://dx.doi.org/10.5114/aoms.2012.28548