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Mechanical ventilation with high tidal volumes attenuates myocardial dysfunction by decreasing cardiac edema in a rat model of LPS-induced peritonitis

BACKGROUND: Injurious mechanical ventilation (MV) may augment organ injury remote from the lungs. During sepsis, myocardial dysfunction is common and increased endothelial activation and permeability can cause myocardial edema, which may, among other factors, hamper myocardial function. We investiga...

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Detalles Bibliográficos
Autores principales: Smeding, Lonneke, Plötz, Frans B, Lamberts, Regis R, van der Laarse, Willem J, Kneyber, Martin CJ, Groeneveld, AB Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361474/
https://www.ncbi.nlm.nih.gov/pubmed/22433071
http://dx.doi.org/10.1186/1465-9921-13-23