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Mechanical ventilation with high tidal volumes attenuates myocardial dysfunction by decreasing cardiac edema in a rat model of LPS-induced peritonitis
BACKGROUND: Injurious mechanical ventilation (MV) may augment organ injury remote from the lungs. During sepsis, myocardial dysfunction is common and increased endothelial activation and permeability can cause myocardial edema, which may, among other factors, hamper myocardial function. We investiga...
Autores principales: | Smeding, Lonneke, Plötz, Frans B, Lamberts, Regis R, van der Laarse, Willem J, Kneyber, Martin CJ, Groeneveld, AB Johan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361474/ https://www.ncbi.nlm.nih.gov/pubmed/22433071 http://dx.doi.org/10.1186/1465-9921-13-23 |
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