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M(4 )muscarinic receptor knockout mice display abnormal social behavior and decreased prepulse inhibition

BACKGROUND: In the central nervous system (CNS), the muscarinic system plays key roles in learning and memory, as well as in the regulation of many sensory, motor, and autonomic processes, and is thought to be involved in the pathophysiology of several major diseases of the CNS, such as Alzheimer�...

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Detalles Bibliográficos
Autores principales: Koshimizu, Hisatsugu, Leiter, Lorene M, Miyakawa, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361477/
https://www.ncbi.nlm.nih.gov/pubmed/22463818
http://dx.doi.org/10.1186/1756-6606-5-10