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Dynamic regulatory on/off minimization for biological systems under internal temporal perturbations
BACKGROUND: Flux balance analysis (FBA) together with its extension, dynamic FBA, have proven instrumental for analyzing the robustness and dynamics of metabolic networks by employing only the stoichiometry of the included reactions coupled with adequately chosen objective function. In addition, und...
Autores principales: | Kleessen, Sabrina, Nikoloski, Zoran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361480/ https://www.ncbi.nlm.nih.gov/pubmed/22409942 http://dx.doi.org/10.1186/1752-0509-6-16 |
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