Pharmacokinetic Models for FcRn-Mediated IgG Disposition

The objectives were to review available PK models for saturable FcRn-mediated IgG disposition, and to explore an alternative semimechanistic model. Most available empirical and mechanistic PK models assumed equal IgG concentrations in plasma and endosome in addition to other model-specific assumptio...

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Detalles Bibliográficos
Autor principal: Xiao, Jim J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361741/
https://www.ncbi.nlm.nih.gov/pubmed/22665983
http://dx.doi.org/10.1155/2012/282989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361741/
https://www.ncbi.nlm.nih.gov/pubmed/22665983
http://dx.doi.org/10.1155/2012/282989

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