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The Neuroinflammatory Response in ALS: The Roles of Microglia and T Cells

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by upper and lower motoneuron death. Mutations in the gene for superoxide dismutase 1 (SOD1) cause a familial form of ALS and have been used to develop transgenic mice which overexpress human mutant SOD1 (mSOD) an...

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Detalles Bibliográficos
Autores principales: Lewis, Coral-Ann, Manning, John, Rossi, Fabio, Krieger, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362167/
https://www.ncbi.nlm.nih.gov/pubmed/22666587
http://dx.doi.org/10.1155/2012/803701