Tirapazamine-Doxorubicin Interaction Referring to Heart Oxidative Stress and Ca(2+) Balance Protein Levels

Doxorubicin (DOX) causes long-term cardiomyopathy that is dependent on oxidative stress and contractility disorders. Tirapazamine (TP), an experimental adjuvant drug, passes the same red-ox transformation as DOX. The aim of the study was to evaluate an effect of tirapazamine on oxidative stress, con...

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Detalles Bibliográficos
Autores principales: Sliwinska, Justyna, Dudka, Jaroslaw, Korga, Agnieszka, Burdan, Franciszek, Matysiak, Wlodzimierz, Jodlowska-Jedrych, Barbara, Mandziuk, Slawomir, Dawidek-Pietryka, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxidative Medicine and Cellular Longevity 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362211/
https://www.ncbi.nlm.nih.gov/pubmed/22666522
http://dx.doi.org/10.1155/2012/890826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362211/
https://www.ncbi.nlm.nih.gov/pubmed/22666522
http://dx.doi.org/10.1155/2012/890826

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