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Asthmatic airway smooth muscle CXCL10 production: mitogen-activated protein kinase JNK involvement

CXCL10 (IP10) is involved in mast cell migration to airway smooth muscle (ASM) bundles in asthma. We aimed to investigate the role of cytokine-induced MAPK activation in CXCL10 production by ASM cells from people with and without asthma. Confluent growth-arrested ASM cells were treated with inhibito...

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Detalles Bibliográficos
Autores principales: Alrashdan, Yazan A., Alkhouri, Hatem, Chen, Emily, Lalor, Daniel J., Poniris, Maree, Henness, Sheridan, Brightling, Christopher E., Burgess, Janette K., Armour, Carol L., Ammit, Alaina J., Margaret Hughes, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362261/
https://www.ncbi.nlm.nih.gov/pubmed/22387292
http://dx.doi.org/10.1152/ajplung.00232.2011