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Comparison of KRAS Mutation Assessment in Tumor DNA and Circulating Free DNA in Plasma and Serum Samples

Testing for mutations in the KRAS oncogene for patients with metastatic colorectal cancer (mCRC) is generally performed using DNA from formalin-fixed paraffin-embedded tumor tissue; however, access to specimens can be limited and analysis challenging. This study assessed the identification of KRAS m...

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Detalles Bibliográficos
Autores principales: Morgan, Shethah R., Whiteley, Jessica, Donald, Emma, Smith, John, Eisenberg, Marcia T., Kallam, Eddie, Kam-Morgan, Lauren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362326/
https://www.ncbi.nlm.nih.gov/pubmed/22661904
http://dx.doi.org/10.4137/CPath.S8798