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Glutathione/thioredoxin systems modulate mitochondrial H(2)O(2) emission: An experimental-computational study

The net emission of hydrogen peroxide (H(2)O(2)) from mitochondria results from the balance between reactive oxygen species (ROS) continuously generated in the respiratory chain and ROS scavenging. The relative contribution of the two major antioxidant systems in the mitochondrial matrix, glutathion...

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Detalles Bibliográficos
Autores principales: Aon, Miguel Antonio, Stanley, Brian Alan, Sivakumaran, Vidhya, Kembro, Jackelyn Melissa, O'Rourke, Brian, Paolocci, Nazareno, Cortassa, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362521/
https://www.ncbi.nlm.nih.gov/pubmed/22585969
http://dx.doi.org/10.1085/jgp.201210772