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Glutathione/thioredoxin systems modulate mitochondrial H(2)O(2) emission: An experimental-computational study
The net emission of hydrogen peroxide (H(2)O(2)) from mitochondria results from the balance between reactive oxygen species (ROS) continuously generated in the respiratory chain and ROS scavenging. The relative contribution of the two major antioxidant systems in the mitochondrial matrix, glutathion...
Autores principales: | Aon, Miguel Antonio, Stanley, Brian Alan, Sivakumaran, Vidhya, Kembro, Jackelyn Melissa, O'Rourke, Brian, Paolocci, Nazareno, Cortassa, Sonia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362521/ https://www.ncbi.nlm.nih.gov/pubmed/22585969 http://dx.doi.org/10.1085/jgp.201210772 |
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