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Localization of the Drosophila Rad9 Protein to the Nuclear Membrane Is Regulated by the C-Terminal Region and Is Affected in the Meiotic Checkpoint

Rad9, Rad1, and Hus1 (9-1-1) are part of the DNA integrity checkpoint control system. It was shown previously that the C-terminal end of the human Rad9 protein, which contains a nuclear localization sequence (NLS) nearby, is critical for the nuclear transport of Rad1 and Hus1. In this study, we show...

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Detalles Bibliográficos
Autores principales: Kadir, Rotem, Bakhrat, Anna, Tokarsky, Ronit, Abdu, Uri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362529/
https://www.ncbi.nlm.nih.gov/pubmed/22666434
http://dx.doi.org/10.1371/journal.pone.0038010