Flexibility in MuA Transposase Family Protein Structures: Functional Mapping with Scanning Mutagenesis and Sequence Alignment of Protein Homologues

MuA transposase protein is a member of the retroviral integrase superfamily (RISF). It catalyzes DNA cleavage and joining reactions via an initial assembly and subsequent structural transitions of a protein-DNA complex, known as the Mu transpososome, ultimately attaching transposon DNA to non-specif...

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Detalles Bibliográficos
Autores principales: Rasila, Tiina S., Vihinen, Mauno, Paulin, Lars, Haapa-Paananen, Saija, Savilahti, Harri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362531/
https://www.ncbi.nlm.nih.gov/pubmed/22666413
http://dx.doi.org/10.1371/journal.pone.0037922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362531/
https://www.ncbi.nlm.nih.gov/pubmed/22666413
http://dx.doi.org/10.1371/journal.pone.0037922

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