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Synchronizing Allelic Effects of Opposing Quantitative Trait Loci Confirmed a Major Epistatic Interaction Affecting Acute Lung Injury Survival in Mice

Increased oxygen (O(2)) levels help manage severely injured patients, but too much for too long can cause acute lung injury (ALI), acute respiratory distress syndrome (ARDS) and even death. In fact, continuous hyperoxia has become a prototype in rodents to mimic salient clinical and pathological cha...

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Detalles Bibliográficos
Autores principales: Prows, Daniel R., Gibbons, William J., Burzynski, Benjamin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362546/
https://www.ncbi.nlm.nih.gov/pubmed/22666475
http://dx.doi.org/10.1371/journal.pone.0038177