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Inhibition of Soluble Tumor Necrosis Factor Ameliorates Synaptic Alterations and Ca(2+) Dysregulation in Aged Rats
The role of tumor necrosis factor α (TNF) in neural function has been investigated extensively in several neurodegenerative conditions, but rarely in brain aging, where cognitive and physiologic changes are milder and more variable. Here, we show that protein levels for TNF receptor 1 (TNFR1) are si...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362564/ https://www.ncbi.nlm.nih.gov/pubmed/22666474 http://dx.doi.org/10.1371/journal.pone.0038170 |