Inhibition of Soluble Tumor Necrosis Factor Ameliorates Synaptic Alterations and Ca(2+) Dysregulation in Aged Rats

The role of tumor necrosis factor α (TNF) in neural function has been investigated extensively in several neurodegenerative conditions, but rarely in brain aging, where cognitive and physiologic changes are milder and more variable. Here, we show that protein levels for TNF receptor 1 (TNFR1) are si...

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Detalles Bibliográficos
Autores principales: Sama, Diana M., Mohmmad Abdul, Hafiz, Furman, Jennifer L., Artiushin, Irina A., Szymkowski, David E., Scheff, Stephen W., Norris, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362564/
https://www.ncbi.nlm.nih.gov/pubmed/22666474
http://dx.doi.org/10.1371/journal.pone.0038170

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