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Down-Regulation of Neogenin Accelerated Glioma Progression through Promoter Methylation and Its Overexpression in SHG-44 Induced Apoptosis

BACKGROUND: Dependence receptors have been proved to act as tumor suppressors in tumorigenesis. Neogenin, a DCC homologue, well known for its fundamental role in axon guidance and cellular differentiation, is also a dependence receptor functioning to control apoptosis. However, loss of neogenin has...

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Detalles Bibliográficos
Autores principales: Wu, Xinmin, Li, Yunqian, Wan, Xilin, Kayira, Tabitha Mlowoka, Cao, Rangjuan, Ju, Xingda, Zhu, Xiaojuan, Zhao, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362578/
https://www.ncbi.nlm.nih.gov/pubmed/22666451
http://dx.doi.org/10.1371/journal.pone.0038074