Tumour Cell Generation of Inducible Regulatory T-Cells in Multiple Myeloma Is Contact-Dependent and Antigen-Presenting Cell-Independent

Regulatory T-cells (T(Reg) cells) are increased in patients with multiple myeloma (MM). We investigated whether MM cells could generate and/or expand T(Reg) cells as a method of immuno-surveillance avoidance. In an in vitro model, CD4(+)CD25(-) FoxP3 (-) T-cells co-cultured with malignant plasma cel...

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Detalles Bibliográficos
Autores principales: Feyler, Sylvia, Scott, Gina B., Parrish, Christopher, Jarmin, Sarah, Evans, Paul, Short, Mike, McKinley, Katherine, Selby, Peter J., Cook, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362588/
https://www.ncbi.nlm.nih.gov/pubmed/22666318
http://dx.doi.org/10.1371/journal.pone.0035981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362588/
https://www.ncbi.nlm.nih.gov/pubmed/22666318
http://dx.doi.org/10.1371/journal.pone.0035981

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