Genome-Wide Expression Analysis Identifies a Modulator of Ionizing Radiation-Induced p53-Independent Apoptosis in Drosophila melanogaster

Tumor suppressor p53 plays a key role in DNA damage responses in metazoa, yet more than half of human tumors show p53 deficiencies. Therefore, understanding how therapeutic genotoxins such as ionizing radiation (IR) can elicit DNA damage responses in a p53-independent manner is of clinical importanc...

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Detalles Bibliográficos
Autores principales: van Bergeijk, Petra, Heimiller, Joseph, Uyetake, Lyle, Su, Tin Tin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362589/
https://www.ncbi.nlm.nih.gov/pubmed/22666323
http://dx.doi.org/10.1371/journal.pone.0036539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362589/
https://www.ncbi.nlm.nih.gov/pubmed/22666323
http://dx.doi.org/10.1371/journal.pone.0036539

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