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Open-label, phase I, pharmacokinetic studies of abiraterone acetate in healthy men
PURPOSE: To evaluate pharmacokinetics, safety, and tolerability of abiraterone acetate (AA) in healthy men. METHODS: Two phase I studies (dose-escalation study and dose-proportionality study) were conducted in healthy men aged 18–55 years. All subjects received 4 consecutive single doses of AA (250,...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362727/ https://www.ncbi.nlm.nih.gov/pubmed/22526411 http://dx.doi.org/10.1007/s00280-012-1865-3 |