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Open-label, phase I, pharmacokinetic studies of abiraterone acetate in healthy men

PURPOSE: To evaluate pharmacokinetics, safety, and tolerability of abiraterone acetate (AA) in healthy men. METHODS: Two phase I studies (dose-escalation study and dose-proportionality study) were conducted in healthy men aged 18–55 years. All subjects received 4 consecutive single doses of AA (250,...

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Detalles Bibliográficos
Autores principales: Acharya, M., Bernard, A., Gonzalez, M., Jiao, J., De Vries, R., Tran, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362727/
https://www.ncbi.nlm.nih.gov/pubmed/22526411
http://dx.doi.org/10.1007/s00280-012-1865-3