Methylation profiling of Epstein-Barr virus immediate-early gene promoters, BZLF1 and BRLF1 in tumors of epithelial, NK- and B-cell origins

BACKGROUND: Epstein-Barr virus (EBV) establishes its latency in EBV-associated malignancies, accompanied by occasionally reactivated lytic cycle. Promoter CpG methylation of EBV genome plays an essential role in maintaining viral latency. Two immediate-early (IE) genes, BZLF1 and BRLF1, induce the s...

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Detalles Bibliográficos
Autores principales: Li, Lili, Su, Xianwei, Choi, Gigi Ching Gee, Cao, Ya, Ambinder, Richard F, Tao, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362778/
https://www.ncbi.nlm.nih.gov/pubmed/22458933
http://dx.doi.org/10.1186/1471-2407-12-125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362778/
https://www.ncbi.nlm.nih.gov/pubmed/22458933
http://dx.doi.org/10.1186/1471-2407-12-125

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