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Regulation of ENaC-mediated alveolar fluid clearance by insulin via PI3K/Akt pathway in LPS-induced acute lung injury
BACKGROUND: Stimulation of epithelial sodium channel (ENaC) increases Na(+ )transport, a driving force of alveolar fluid clearance (AFC) to keep alveolar spaces free of edema fluid that is beneficial for acute lung injury (ALI). It is well recognized that regulation of ENaC by insulin via PI3K pathw...
Autores principales: | Deng, Wang, Li, Chang-Yi, Tong, Jin, Zhang, Wei, Wang, Dao-Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362779/ https://www.ncbi.nlm.nih.gov/pubmed/22458687 http://dx.doi.org/10.1186/1465-9921-13-29 |
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