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Extension of Chronological Lifespan by Hexokinase Mutation in Kluyveromyces lactis Involves Increased Level of the Mitochondrial Chaperonin Hsp60

Oxidative damage, mitochondrial dysfunction, genomic instability, and telomere shortening represent all molecular processes proposed as causal factors in aging. Lifespan can be increased by metabolism through an influence on such processes. Glucose reduction extends chronological lifespan (CLS) of S...

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Detalles Bibliográficos
Autores principales: Rizzetto, Lisa, Zanni, Elena, Uccelletti, Daniela, Ferrero, Ileana, Goffrini, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362934/
https://www.ncbi.nlm.nih.gov/pubmed/22675632
http://dx.doi.org/10.1155/2012/946586