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Extension of Chronological Lifespan by Hexokinase Mutation in Kluyveromyces lactis Involves Increased Level of the Mitochondrial Chaperonin Hsp60
Oxidative damage, mitochondrial dysfunction, genomic instability, and telomere shortening represent all molecular processes proposed as causal factors in aging. Lifespan can be increased by metabolism through an influence on such processes. Glucose reduction extends chronological lifespan (CLS) of S...
Autores principales: | Rizzetto, Lisa, Zanni, Elena, Uccelletti, Daniela, Ferrero, Ileana, Goffrini, Paola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362934/ https://www.ncbi.nlm.nih.gov/pubmed/22675632 http://dx.doi.org/10.1155/2012/946586 |
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