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Photoswitchable Nanoparticles for Triggered Tissue Penetration and Drug Delivery

[Image: see text] We report a novel nanoparticulate drug delivery system that undergoes reversible volume change from 150 to 40 nm upon phototriggering with UV light. The volume change of these monodisperse nanoparticles comprising spiropyran, which undergoes reversible photoisomerization, and PEGyl...

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Detalles Bibliográficos
Autores principales: Tong, Rong, Hemmati, Houman D., Langer, Robert, Kohane, Daniel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3363369/
https://www.ncbi.nlm.nih.gov/pubmed/22385538
http://dx.doi.org/10.1021/ja211888a