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Hypoxia-inducible factor 1 protects hypoxic astrocytes against glutamate toxicity
Stroke is a major neurological disorder characterized by an increase in the Glu (glutamate) concentration resulting in excitotoxicity and eventually cellular damage and death in the brain. HIF-1 (hypoxia-inducible factor-1), a transcription factor, plays an important protective role in promoting cel...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Neurochemistry
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3363983/ https://www.ncbi.nlm.nih.gov/pubmed/22540931 http://dx.doi.org/10.1042/AN20120006 |