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Overexpression of DNA damage-induced 45 α gene contributes to esophageal squamous cell cancer by promoter hypomethylation

BACKGROUND: Environmental factors-induced dysfunction of esophageal squamous epithelium, including genomic DNA impairment and apoptosis, play an important role in the pathogenesis of esophageal squamous cell cancer. DNA damage-induced 45α (GADD45α) has been found promoting DNA repair and removing me...

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Detalles Bibliográficos
Autores principales: Wang, Bao xiang, Yin, Bang Liang, He, Bin, Chen, Chen, Zhao, Ming, Zhang, Wei xing, Xia, Zhen Kun, Pan, Yi zhi, Tang, Jing qun, Zhou, Xin min, Yin, Ni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364148/
https://www.ncbi.nlm.nih.gov/pubmed/22313682
http://dx.doi.org/10.1186/1756-9966-31-11