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NHERF1 acts as a molecular switch to program metastatic behavior and organotropism via its PDZ domains

Metastatic cells are highly plastic for differential expression of tumor phenotype hallmarks and metastatic organotropism. The signaling proteins orchestrating the shift of one cell phenotype and organ pattern to another are little known. Na(+)/H(+) exchanger regulatory factor (NHERF1) is a molecula...

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Detalles Bibliográficos
Autores principales:	Cardone, Rosa Angela, Greco, Maria Raffaella, Capulli, Mattia, Weinman, Edward J., Busco, Giovanni, Bellizzi, Antonia, Casavola, Valeria, Antelmi, Ester, Ambruosi, Barbara, Dell'Aquila, Maria Elena, Paradiso, Angelo, Teti, Anna, Rucci, Nadia, Reshkin, Stephan Joel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364169/ https://www.ncbi.nlm.nih.gov/pubmed/22496422 http://dx.doi.org/10.1091/mbc.E11-11-0911

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