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Lamin B1 loss is a senescence-associated biomarker
Cellular senescence is a potent tumor-suppressive mechanism that arrests cell proliferation and has been linked to aging. However, studies of senescence have been impeded by the lack of simple, exclusive biomarkers of the senescent state. Senescent cells develop characteristic morphological changes,...
Autores principales: | Freund, Adam, Laberge, Remi-Martin, Demaria, Marco, Campisi, Judith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364172/ https://www.ncbi.nlm.nih.gov/pubmed/22496421 http://dx.doi.org/10.1091/mbc.E11-10-0884 |
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