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APC and Smad7 link TGFβ type I receptors to the microtubule system to promote cell migration

Cell migration occurs by activation of complex regulatory pathways that are spatially and temporally integrated in response to extracellular cues. Binding of adenomatous polyposis coli (APC) to the microtubule plus ends in polarized cells is regulated by glycogen synthase kinase 3β (GSK-3β). This ev...

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Detalles Bibliográficos
Autores principales: Ekman, Maria, Mu, Yabing, Lee, So Young, Edlund, Sofia, Kozakai, Takaharu, Thakur, Noopur, Tran, Hoanh, Qian, Jiang, Groeden, Joanna, Heldin, Carl-Henrik, Landström, Maréne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364175/
https://www.ncbi.nlm.nih.gov/pubmed/22496417
http://dx.doi.org/10.1091/mbc.E10-12-1000