Structure of Shroom domain 2 reveals a three-segmented coiled-coil required for dimerization, Rock binding, and apical constriction

Shroom (Shrm) proteins are essential regulators of cell shape and tissue morpho­logy during animal development that function by interacting directly with the coiled-coil region of Rho kinase (Rock). The Shrm–Rock interaction is sufficient to direct Rock subcellular localization and the subsequent as...

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Detalles Bibliográficos
Autores principales: Mohan, Swarna, Rizaldy, Ryan, Das, Debamitra, Bauer, Robert J., Heroux, Annie, Trakselis, Michael A., Hildebrand, Jeffrey D., VanDemark, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364177/
https://www.ncbi.nlm.nih.gov/pubmed/22493320
http://dx.doi.org/10.1091/mbc.E11-11-0937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364177/
https://www.ncbi.nlm.nih.gov/pubmed/22493320
http://dx.doi.org/10.1091/mbc.E11-11-0937

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