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An In Situ Autologous Tumor Vaccination with Combined Radiation Therapy and TLR9 Agonist Therapy

PURPOSE: Recent studies have shown that a new generation of synthetic agonist of Toll-like receptor (TLR) 9 consisting a 3′-3′-attached structure and a dCp7-deaza-dG dinucultodie shows more potent immunostimulatory effects in both mouse and human than conventional CpG oligonucleotides. Radiation the...

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Detalles Bibliográficos
Autores principales: Zhang, Huagang, Liu, Laibin, Yu, Dong, Kandimalla, Ekambar R., Sun, Hui Bin, Agrawal, Sudhir, Guha, Chandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364192/
https://www.ncbi.nlm.nih.gov/pubmed/22666458
http://dx.doi.org/10.1371/journal.pone.0038111