Cargando…
Fractionation of a Herbal Antidiarrheal Medicine Reveals Eugenol as an Inhibitor of Ca(2+)-Activated Cl(−) Channel TMEM16A
The Ca(2+)-activated Cl(−) channel TMEM16A is involved in epithelial fluid secretion, smooth muscle contraction and neurosensory signaling. We identified a Thai herbal antidiarrheal formulation that inhibited TMEM16A Cl(−) conductance. C18-reversed-phase HPLC fractionation of the herbal formulation...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364195/ https://www.ncbi.nlm.nih.gov/pubmed/22666439 http://dx.doi.org/10.1371/journal.pone.0038030 |