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BRCA2 Mutations and Triple-Negative Breast Cancer

Recently, BRCA1 germline mutations were found in a high proportion (14–34%) of patients with triple-negative breast cancer (TNBC). BRCA2 was either not analyzed or showed much lower mutation frequencies. Therefore, we screened a group of TNBC patients (n = 30) of white European descent for mutations...

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Detalles Bibliográficos
Autores principales: Meyer, Peter, Landgraf, Katharina, Högel, Bernhard, Eiermann, Wolfgang, Ataseven, Beyhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364210/
https://www.ncbi.nlm.nih.gov/pubmed/22666503
http://dx.doi.org/10.1371/journal.pone.0038361