Genome-Wide Study of Gene Variants Associated with Differential Cardiovascular Event Reduction by Pravastatin Therapy

Statin therapy reduces the risk of coronary heart disease (CHD), however, the person-to-person variability in response to statin therapy is not well understood. We have investigated the effect of genetic variation on the reduction of CHD events by pravastatin. First, we conducted a genome-wide assoc...

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Detalles Bibliográficos
Autores principales: Shiffman, Dov, Trompet, Stella, Louie, Judy Z., Rowland, Charles M., Catanese, Joseph J., Iakoubova, Olga A., Kirchgessner, Todd G., Westendorp, Rudi G. J., de Craen, Anton J. M., Slagboom, P. Eline, Buckley, Brendan M., Stott, David J., Sattar, Naveed, Devlin, James J., Packard, Christopher J., Ford, Ian, Sacks, Frank M., Jukema, J. Wouter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364212/
https://www.ncbi.nlm.nih.gov/pubmed/22666496
http://dx.doi.org/10.1371/journal.pone.0038240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364212/
https://www.ncbi.nlm.nih.gov/pubmed/22666496
http://dx.doi.org/10.1371/journal.pone.0038240

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