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Genome-Wide Study of Gene Variants Associated with Differential Cardiovascular Event Reduction by Pravastatin Therapy
Statin therapy reduces the risk of coronary heart disease (CHD), however, the person-to-person variability in response to statin therapy is not well understood. We have investigated the effect of genetic variation on the reduction of CHD events by pravastatin. First, we conducted a genome-wide assoc...
Autores principales: | Shiffman, Dov, Trompet, Stella, Louie, Judy Z., Rowland, Charles M., Catanese, Joseph J., Iakoubova, Olga A., Kirchgessner, Todd G., Westendorp, Rudi G. J., de Craen, Anton J. M., Slagboom, P. Eline, Buckley, Brendan M., Stott, David J., Sattar, Naveed, Devlin, James J., Packard, Christopher J., Ford, Ian, Sacks, Frank M., Jukema, J. Wouter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364212/ https://www.ncbi.nlm.nih.gov/pubmed/22666496 http://dx.doi.org/10.1371/journal.pone.0038240 |
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