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ATP-Sensitive Potassium Channels Exhibit Variance in the Number of Open Channels below the Limit Predicted for Identical and Independent Gating

In small cells containing small numbers of ion channels, noise due to stochastic channel opening and closing can introduce a substantial level of variability into the cell's membrane potential. Negatively cooperative interactions that couple a channel's gating conformational change to the...

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Detalles Bibliográficos
Autores principales: Choi, Kee-Hyun, Licht, Stuart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364246/
https://www.ncbi.nlm.nih.gov/pubmed/22666353
http://dx.doi.org/10.1371/journal.pone.0037399