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Abnormal Wnt and PI3Kinase Signaling in the Malformed Intestine of lama5 Deficient Mice
Laminins are major constituents of basement membranes and are essential for tissue homeostasis. Laminin-511 is highly expressed in the intestine and its absence causes severe malformation of the intestine and embryonic lethality. To understand the mechanistic role of laminin-511 in tissue homeostasi...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364287/ https://www.ncbi.nlm.nih.gov/pubmed/22666383 http://dx.doi.org/10.1371/journal.pone.0037710 |