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Towards a Molecular Understanding of the Fanconi Anemia Core Complex

Fanconi Anemia (FA) is a genetic disorder characterized by the inability of patient cells to repair DNA damage caused by interstrand crosslinking agents. There are currently 14 verified FA genes, where mutation of any single gene prevents repair of DNA interstrand crosslinks (ICLs). The accumulation...

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Detalles Bibliográficos
Autores principales: Hodson, Charlotte, Walden, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364535/
https://www.ncbi.nlm.nih.gov/pubmed/22675617
http://dx.doi.org/10.1155/2012/926787