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Molecular Dynamics Simulation of HIV Fusion Inhibitor T-1249: Insights on Peptide-Lipid Interaction

T-1249 is a peptide that inhibits the fusion of HIV envelope with the target cell membrane. Recent results indicate that T-1249, as in the case of related inhibitor peptide T-20 (enfuvirtide), interacts with membranes, more extensively in the bilayer liquid disordered phase than in the liquid ordere...

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Detalles Bibliográficos
Autores principales: Martins do Canto, A. M. T., Palace Carvalho, A. J., Prates Ramalho, J. P., Loura, Luís M. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364549/
https://www.ncbi.nlm.nih.gov/pubmed/22675399
http://dx.doi.org/10.1155/2012/151854