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Microglial KCa3.1 Channels as a Potential Therapeutic Target for Alzheimer's Disease

There exists an urgent need for new target discovery to treat Alzheimer's disease (AD); however, recent clinical trials based on anti-Aβ and anti-inflammatory strategies have yielded disappointing results. To expedite new drug discovery, we propose reposition targets which have been previously...

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Detalles Bibliográficos
Autores principales: Maezawa, Izumi, Jenkins, David Paul, Jin, Benjamin E., Wulff, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364551/
https://www.ncbi.nlm.nih.gov/pubmed/22675649
http://dx.doi.org/10.1155/2012/868972