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Early Blockade of TLRs MyD88-Dependent Pathway May Reduce Secondary Spinal Cord Injury in the Rats

To determine the role of toll-like receptors (TLRs) myeloid differentiation factor 88 (MyD88) dependent pathway in the spinal cord secondary injury, compression injury was made at T8 segment of the spinal cord in adult male Sprague-Dawley rats. Shown by RT-PCR, TLR4 mRNA in the spinal cord was quick...

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Detalles Bibliográficos
Autores principales: Yao, An-hui, Jia, Li-yun, Zhang, Yu-kai, Ma, Quan-rui, Cheng, Peng, Liu, Ling, Ju, Gong, Kuang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364571/
https://www.ncbi.nlm.nih.gov/pubmed/22675384
http://dx.doi.org/10.1155/2012/591298