Novel repressor regulates insulin sensitivity through interaction with Foxo1

Forkhead box-containing protein o (Foxo) 1 is a key transcription factor in insulin and glucose metabolism. We identified a Foxo1-CoRepressor (FCoR) protein in mouse adipose tissue that inhibits Foxo1’s activity by enhancing acetylation via impairment of the interaction between Foxo1 and the deacety...

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Detalles Bibliográficos
Autores principales: Nakae, Jun, Cao, Yongheng, Hakuno, Fumihiko, Takemori, Hiroshi, Kawano, Yoshinaga, Sekioka, Risa, Abe, Takaya, Kiyonari, Hiroshi, Tanaka, Toshiya, Sakai, Juro, Takahashi, Shin-Ichiro, Itoh, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364737/
https://www.ncbi.nlm.nih.gov/pubmed/22510882
http://dx.doi.org/10.1038/emboj.2012.97

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364737/
https://www.ncbi.nlm.nih.gov/pubmed/22510882
http://dx.doi.org/10.1038/emboj.2012.97

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