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Novel repressor regulates insulin sensitivity through interaction with Foxo1
Forkhead box-containing protein o (Foxo) 1 is a key transcription factor in insulin and glucose metabolism. We identified a Foxo1-CoRepressor (FCoR) protein in mouse adipose tissue that inhibits Foxo1’s activity by enhancing acetylation via impairment of the interaction between Foxo1 and the deacety...
Autores principales: | Nakae, Jun, Cao, Yongheng, Hakuno, Fumihiko, Takemori, Hiroshi, Kawano, Yoshinaga, Sekioka, Risa, Abe, Takaya, Kiyonari, Hiroshi, Tanaka, Toshiya, Sakai, Juro, Takahashi, Shin-Ichiro, Itoh, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364737/ https://www.ncbi.nlm.nih.gov/pubmed/22510882 http://dx.doi.org/10.1038/emboj.2012.97 |
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