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Characterization of a pneumococcal meningitis mouse model

BACKGROUND: S. pneumoniae is the most common causative agent of meningitis, and is associated with high morbidity and mortality. We aimed to develop an integrated and representative pneumococcal meningitis mouse model resembling the human situation. METHODS: Adult mice (C57BL/6) were inoculated in t...

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Detalles Bibliográficos
Autores principales: Mook-Kanamori, Barry, Geldhoff, Madelijn, Troost, Dirk, van der Poll, Tom, van de Beek, Diederik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364848/
https://www.ncbi.nlm.nih.gov/pubmed/22455545
http://dx.doi.org/10.1186/1471-2334-12-71