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The complete genome sequence of the acarbose producer Actinoplanes sp. SE50/110

BACKGROUND: Actinoplanes sp. SE50/110 is known as the wild type producer of the alpha-glucosidase inhibitor acarbose, a potent drug used worldwide in the treatment of type-2 diabetes mellitus. As the incidence of diabetes is rapidly rising worldwide, an ever increasing demand for diabetes drugs, suc...

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Detalles Bibliográficos
Autores principales: Schwientek, Patrick, Szczepanowski, Rafael, Rückert, Christian, Kalinowski, Jörn, Klein, Andreas, Selber, Klaus, Wehmeier, Udo F, Stoye, Jens, Pühler, Alfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364876/
https://www.ncbi.nlm.nih.gov/pubmed/22443545
http://dx.doi.org/10.1186/1471-2164-13-112